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Home >> Antibodies >> RAP1A Antibody / KREV1

RAP1A Antibody / KREV1 (R32160)

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  Catalog No Formulation Size Price (USD)  
Image R32160 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat 1) heart, 2) lung, 3) stomach, 4) kidney and mouse 5) heart, 6) lung, 7) stomach and 8) kidney lysate with RAP1A antibody. Expected molecular weight ~21 kDa.
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Western blot testing of rat 1) heart, 2) lung, 3) stomach, 4) kidney and mouse 5) heart, 6) lung, 7) stomach and 8) kidney lysate with RAP1A antibody. Expected molecular weight ~21 kDa.
Western blot testing of 1) rat brain, 2) rat liver, 3) rat kidney, 4) human MCF7 and 5) human SW620 lysate with RAPA1 antibody. Expected molecular weight ~21 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P62834
Applications Western blot : 0.1-0.5ug/ml
Limitations This RAP1A antibody is available for research use only.
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Description

Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the RAP1A antibody should be determined by the researcher.

Immunogen

Amino acids EIFYDLVRQINRKTPVEKKKPKKKSC of human Ras-related protein Rap-1A were used as the immunogen for the RAP1A antibody.

Storage

After reconstitution, the RAP1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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