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Home >> Antibodies >> RANKL Antibody / TNFSF11

RANKL Antibody / TNFSF11 (F51413)

  Catalog No Formulation Size Price (USD)  
Image F51413-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F51413-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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RANKL antibody flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Western blot analysis of RANKL antibody and HL-60 lysate
IHC analysis of FFPE human skeletal muscle stained with RANKL antibody
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt O14788
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This RANKL antibody is available for research use only.
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  • Applications : WB, ELISA (protein)
    Reactivity : Mouse, Rat

Description

TNFSF11 is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response.

Application Notes

Titration of the RANKL antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this RANKL antibody.

Storage

Aliquot the RANKL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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