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Home >> Antibodies >> RANK Antibody

RANK Antibody (R31815)

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  Catalog No Formulation Size Price (USD)  
Image R31815 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 419
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Western blot testing of mouse Hepa1-6 cell lysate with RANK antibody. Predicted molecular weight ~66 kDa, routinely observed at 80~100 kDa.
Western blot testing of mouse Hepa1-6 cell lysate with RANK antibody. Predicted molecular weight ~66 kDa, routinely observed at 80~100 kDa.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt O35305
Applications Western blot : 0.1-0.5ug/ml
ELISA : 0.1-0.5ug/ml (mouse protein tested); request BSA-free format for coating
Limitations This RANK antibody is available for research use only.
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Description

Receptor Activator of NFkB (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANKL (Receptor Activator for NFkB Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1.

Application Notes

Optimal dilution of the RANK antibody should be determined by the researcher.

Immunogen

Amino acids 35-214 of mouse RANK were used as the immunogen for the RANK antibody.

Storage

After reconstitution, the RANK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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