- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Rac GTPase-activating protein 1 Antibody / RACGAP1 (F54599)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54599-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54599-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q9H0H5 |
| Localization | Nuclear, cytoplasmic |
| Applications | Western blot : 1:500-1:2000 Immunohistochemistry (FFPE) : 1:25 Immunofluorescence : 1:25 Flow cytometry : 1:25 (1x10e6 cells) |
| Limitations | This Rac GTPase-activating protein 1 antibody is available for research use only. |
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Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
The stated application concentrations are suggested starting points. Titration of the Rac GTPase-activating protein 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 23-50 from the human protein was used as the immunogen for the Rac GTPase-activating protein 1 antibody.
Aliquot the Rac GTPase-activating protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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