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Home >> Antibodies >> PUS7L Antibody / Pseudouridylate synthase 7 homolog-like protein

PUS7L Antibody / Pseudouridylate synthase 7 homolog-like protein (RQ8439)

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  Catalog No Formulation Size Price (USD)  
Image RQ8439 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Western blot testing of human 1) K562, 2) Caco-2 and 3) HEL cell lysate with PUS7L antibody. Predicted molecular weight ~81 kDa.
Western blot testing of human 1) K562, 2) Caco-2 and 3) HEL cell lysate with PUS7L antibody. Predicted molecular weight ~81 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9H0K6
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This PUS7L antibody is available for research use only.
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Description

Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene. PUS7L (pseudouridylate synthase 7 homolog (S. cerevisiae) -like) is a 701 amino acid protein that belongs to the pseudouridine synthase truD family and contains one TRUD domain. The PUS7L gene is conserved in chimpanzee, canine, bovine, mouse, chicken and zebrafish, and maps to human chromosome 12q12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

Application Notes

Optimal dilution of the PUS7L antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (R165-H699) was used as the immunogen for the PUS7L antibody.

Storage

After reconstitution, the PUS7L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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