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Home >> Antibodies >> Purine nucleoside phosphorylase Antibody / PNP / Inosine phosphorylase

Purine nucleoside phosphorylase Antibody / PNP / Inosine phosphorylase [clone 2H10] (RQ6354)

  Catalog No Formulation Size Price (USD)  
Image RQ6354 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human HEK293, 2) human PC-3 and 3) rat spleen lysate with Purine nucleoside phosphorylase antibody. Predicted molecular weight ~32 kDa.
Availability 1-3 business days
Species Reactivity Rat, Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b
Clone Name 2H10
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P00491
Localization Cytoplasmic
Applications Western blot : 0.5-1ug/ml
Limitations This Purine nucleoside phosphorylase antibody is available for research use only.
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Description

The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

Application Notes

Optimal dilution of the Purine nucleoside phosphorylase antibody should be determined by the researcher.

Immunogen

Amino acids AMSDAYDRTMRQRALSTWKQMGEQRELQE were used as the immunogen for the Purine nucleoside phosphorylase antibody.

Storage

After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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