- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PTH Antibody Rabbit Polyclonal / Parathyroid Hormone Antibody / N-Terminal (V3375)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V3375-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
|
V3375-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
|
|
V3375SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Protein A affinity chromatography |
| UniProt | P01270 |
| Localization | Cytoplasmic and secreted |
| Applications | Immunohistochemistry (FFPE) : 0.5-1ug/ml for 30 min at RT |
| Limitations | This PTH antibody is available for research use only. |
|
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Parathyroid hormone (PTH), encoded by the PTH gene, is a peptide hormone secreted by endocrine chief cells of the parathyroid glands and functions as a key regulator of calcium and phosphate homeostasis. Through coordinated actions on bone, kidney, and vitamin D metabolism, PTH maintains systemic mineral balance and supports skeletal physiology. PTH Antibody Rabbit Polyclonal enables detection of Parathyroid hormone expression in endocrine tissues and supports research investigating hormone production and parathyroid gland biology.
PTH is synthesized in parathyroid chief cells as preproparathyroid hormone and subsequently processed intracellularly to generate the mature peptide hormone before secretion into circulation. In tissue sections, Parathyroid hormone is typically localized within the cytoplasm of endocrine cells responsible for hormone synthesis and storage. Detection of this cytoplasmic staining pattern allows visualization of hormone-producing cells within the parathyroid gland and assists researchers studying endocrine cell populations and hormone production in normal physiology.
PTH plays a central role in endocrine regulation of calcium metabolism by stimulating bone resorption, increasing renal calcium reabsorption, and promoting activation of vitamin D in the kidney. Through these coordinated mechanisms, Parathyroid hormone maintains circulating calcium levels within a narrow physiological range. Dysregulation of PTH secretion can contribute to metabolic bone disease and endocrine disorders, making detection of Parathyroid hormone an important component of endocrine and metabolic research.
PTH antibodies are widely used in studies of parathyroid gland biology and endocrine pathology. Immunodetection of Parathyroid hormone supports identification of hormone-producing parathyroid tissue and contributes to research investigating parathyroid adenoma, parathyroid hyperplasia, and parathyroid carcinoma. Because parathyroid tissue can sometimes resemble surrounding thyroid structures morphologically, detection using a PTH antibody provides a useful molecular marker for identifying parathyroid-derived endocrine cells.
This rabbit polyclonal antibody recognizes Parathyroid hormone and supports research investigating hormone expression, endocrine signaling pathways, and parathyroid gland biology. A PTH antibody can be used to detect Parathyroid hormone in endocrine tissues and related experimental models studying calcium regulation and hormone production.
Optimal dilution of the PTH Antibody Rabbit Polyclonal should be determined by the researcher.
A synthetic peptide from the N-terminal region of human Parathyroid hormone was used as the immunogen for the PTH antibody.
Store the PTH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Parathyroid hormone antibody, PTH antibody, PTH protein antibody, Parathyroid hormone protein antibody
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