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Home >> Antibodies >> PTEN Antibody

PTEN Antibody [clone PTEN/7344] (V4110)

  Catalog No Formulation Size Price (USD)  
Image V4110-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 559
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V4110-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 259
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V4110SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 559
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IHC staining of FFPE human prostate carcinoma tissue with PTEN antibody (clone PTEN/7344) at 2ug/ml. Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free PTEN antibody (clone PTEN/7344) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Host Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG, kappa
Clone Name PTEN/7344
Purity Protein A/G affinity
UniProt P60484
Localization Cytoplasm, Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This PTEN antibody is available for research use only.
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Description

PTEN (phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase) contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. It was identified as a tumor suppressor that is mutated in a large number of cancers, including sporadic brain, breast, kidney, and prostate cancers.

For broader research into PTEN expression and tumor suppressor function, explore our PTEN Antibody page for additional reagents targeting phosphatase and tensin homolog.

Application Notes

Optimal dilution of the PTEN antibody should be determined by the researcher.

Immunogen

Recombinant full-length human PTEN protein was used as the immunogen for the PTEN antibody.

Storage

Aliquot the PTEN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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