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Home >> Antibodies >> PSAT1 Antibody / Phosphoserine aminotransferase [Discontinued, view alternative antibodies]

PSAT1 Antibody / Phosphoserine aminotransferase [Discontinued, view alternative antibodies] [clone CPTC-PSAT1-1] (V7282)

  Catalog No Formulation Size Price (USD)  
Image V7282-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 429
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V7282-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 199
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V7282SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 429
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using PSAT1 antibody. These results demonstrate the foremost specificity of the CPTC-PSAT1-1 mAb.
Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free PSAT1 antibody as confirmation of integrity and purity.
Availability Discontinued
Species Reactivity Human. Other species not tested.
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name CPTC-PSAT1-1
Purity Protein G affinity chromatography
UniProt Q9Y617
Localization Nuclear
Applications Western blot : 0.5-1ug/ml
Immunohistochemistry (FFPE) : 0.5-1ug/ml
Limitations This PSAT1 antibody is available for research use only.
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Description

PSAT1 (phosphoserine aminotransferase 1), also known as phosphoserine aminotransferase, phosphohydroxythreonine aminotransferase, endometrial progesterone-induced protein, PSA, PSAT, EPIP or MGC1460, is a 370 amino acid protein belonging to the class-V pyridoxal-phosphate-dependent aminotransferase family and Ser C subfamily. PSAT1 catalyzes the second step in the L-serine synthesis pathway, converting 3-phosphohydroxypyruvate into 3-phosphoserine. While highly expressed in pancreas, brain, kidney and liver, PSAT1 is expressed at very low levels in colon, testis, thymus and prostate. There are two known isoforms of PSAT1 which result from alternative splicing events, and the gene encoding PSAT1 maps to human chromsome 9q21.2. PSAT1 deficiency can cause phosphoserine aminotransferase deficiency (PSATD), whose symptoms include psychomotor retardation, intractable seizures, acquired microcephaly and hypertonia.

Application Notes

Optimal dilution of the PSAT1 antibody should be determined by the researcher.

Immunogen

Full-length recombinant human protein was used as the immunogen for this PSAT1 antibody.

Storage

Store the PSAT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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