- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PSAP Antibody Clone PASE/4LJ / Prostate Specific Acid Phosphatase [clone PASE/4LJ] (V8033)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V8033-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
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V8033-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
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V8033SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | PASE/4LJ |
| Purity | Protein G affinity chromatography |
| UniProt | P15309 |
| Localization | Cytoplasmic |
| Applications | Immunofluorescence : 1-2ug/ml Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This PSAP antibody is available for research use only. |
|
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Prostatic acid phosphatase (ACPP), also known as PAP or Acid phosphatase 3 (ACP3), is a secreted glycoprotein enzyme predominantly expressed by prostate epithelial cells. The protein belongs to the histidine acid phosphatase family and catalyzes the hydrolysis of phosphate esters under acidic conditions. PAP is highly enriched in prostate glandular epithelium and is secreted into seminal fluid, where it contributes to enzymatic activity within the prostate microenvironment. PSAP Antibody Clone PASE/4LJ recognizes this prostate-associated enzyme and enables detection of Prostatic acid phosphatase expression in prostate-derived tissues and prostate cancer models.
PSAP Antibody is widely used in studies examining prostate epithelial differentiation and prostate cancer biology. In tissue-based analyses, Prostatic acid phosphatase expression is typically observed in prostate glandular epithelial cells and prostate tumor cells. Immunohistochemical staining frequently demonstrates cytoplasmic localization within glandular epithelial structures, reflecting the secretory nature of PAP. Detection of ACP3 expression provides a useful approach for identifying prostate epithelial lineage and examining differentiation of prostate-derived tumor cells.
Prostatic acid phosphatase was historically one of the earliest biochemical markers used in studies of prostate cancer before prostate-specific antigen testing became widely adopted. Although PSA later became the dominant clinical marker, PAP remains an important protein in prostate biology research and continues to be examined as a marker of prostate epithelial differentiation. Detection of PAP expression allows investigators to analyze prostate tissue architecture and evaluate molecular characteristics of prostate tumors.
PSAP Antibody Clone PASE/4LJ is a mouse monoclonal antibody developed to recognize Prostatic acid phosphatase in prostate epithelial tissues and prostate cancer models. Antibodies targeting ACP3 are commonly used to study prostate gland biology, prostate tumor development, and prostate epithelial cell identity. Clone PASE/4LJ has been described extensively in the scientific literature, making it one of the widely used antibodies for detecting Prostatic acid phosphatase in prostate-related research applications.
Detection of Prostatic acid phosphatase using PSAP Antibody supports investigations of prostate epithelial lineage markers and prostate cancer biology. Analysis of ACP3 expression helps identify prostate-derived tumor cells and contributes to research examining prostate tumor differentiation and prostate epithelial cell function.
Optimal dilution of the PSAP Antibody Clone PASE/4LJ should be determined by the researcher.
Prostatic acid phosphatase purified from human seminal plasma was used as the immunogen for this PSAP antibody (clone PASE/4LJ).
Store the PSAP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Prostatic acid phosphatase antibody, PAP antibody, ACP3 antibody, ACPP antibody, Prostate acid phosphatase antibody
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