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Home >> Antibodies >> PRTFDC1 Antibody / Phosphoribosyltransferase domain-containing protein 1

PRTFDC1 Antibody / Phosphoribosyltransferase domain-containing protein 1 (RQ8102)

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  Catalog No Formulation Size Price (USD)  
Image RQ8102 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Immunofluorescent staining of FFPE human A431 cells with GNB1 antibody (red) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
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Immunofluorescent staining of FFPE human A431 cells with GNB1 antibody (red) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of 1) human Caco-2, 2) human HeLa, 3) human A549, 4) human K562, 5) rat brain and 6) mouse brain tissue lysate with PRTFDC1 antibody. Predicted molecular weight ~26 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9NRG1
Localization Cytoplasm
Applications Western blot : 0.5-1ug/ml
Immunofluorescence : 5ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This PRTFDC1 antibody is available for research use only.
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Description

This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation.

Application Notes

Optimal dilution of the PRTFDC1 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids E6-V225) was used as the immunogen for the PRTFDC1 antibody.

Storage

After reconstitution, the PRTFDC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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