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Home >> Antibodies >> PRRT2 Antibody

PRRT2 Antibody (F54710)

  Catalog No Formulation Size Price (USD)  
Image F54710-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54710-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of human brain tissue lysate with PRRT2 antibody. Predicted molecular weight ~35 kDa.
Western blot testing of human SH-SY5Y cell lysate with PRRT2 antibody. Predicted molecular weight ~35 kDa.
Western blot testing of human MDA-MB-453 cell lysate with PRRT2 antibody. Predicted molecular weight ~35 kDa.
Flow cytometry testing of fixed and permeabilized human U-2 OS cells with PRRT2 antibody; Blue=isotype control, Green= PRRT2 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt Q7Z6L0
Applications Western blot : 1:500-1:2000
Flow cytometry : 1:25 (1x10e6 cells)
Limitations This PRRT2 antibody is available for research use only.
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Description

As a component of the outer core of AMPAR complex, Proline-rich transmembrane protein 2 may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca2+-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the PRRT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 207-233 from the human protein was used as the immunogen for the PRRT2 antibody.

Storage

Aliquot the PRRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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