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Home >> Antibodies >> PRPF8 Antibody / Pre-mRNA-processing-splicing factor 8

PRPF8 Antibody / Pre-mRNA-processing-splicing factor 8 (RQ8095)

  Catalog No Formulation Size Price (USD)  
Image RQ8095 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human HeLa, 2) human SH-SY5Y and 3) mouse NIH 3T3 cell lysate with PRPF8 antibody. Predicted molecular weight ~274 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q6P2Q9
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This PRPF8 antibody is available for research use only.
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Description

Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene. Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Application Notes

Optimal dilution of the PRPF8 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids E433-H2166) was used as the immunogen for the PRPF8 antibody.

Storage

After reconstitution, the PRPF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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