- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Prostein Antibody / Golgi-Associated Secretory Protein Antibody [clone SLC45A3/4965R] (V9159)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V9159-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V9159-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
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V9159SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | SLC45A3/4965R |
| Purity | Protein A/G affinity |
| UniProt | Q96JT2 |
| Localization | Membrane, Vesicles, Nucleus |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This Prostein antibody is available for research use only. |
|
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Solute carrier family 45 member 3 (SLC45A3), commonly known as Prostein, is a prostate-specific protein encoded by the SLC45A3 gene and localized predominantly to the Golgi apparatus in secretory epithelial cells. Prostein Antibody is used to detect SLC45A3 as a Golgi-associated protein, enabling investigation of intracellular trafficking and secretory pathway organization in prostate tissue and epithelial cell systems.
Prostein antibody, also referred to as SLC45A3 antibody or prostate-specific androgen-regulated protein antibody, exhibits a characteristic perinuclear staining pattern that reflects its localization within the Golgi complex. This spatial distribution provides a clear indicator of Golgi-associated compartments and distinguishes Prostein from proteins with diffuse cytoplasmic or nuclear localization. Its defined intracellular positioning enhances its utility for studies focused on cellular organization and compartmentalization.
The SLC45A3 protein is a member of the solute carrier family and is believed to participate in intracellular transport processes linked to vesicular trafficking within the Golgi network. Although the precise substrates transported by SLC45A3 remain to be fully characterized, its localization suggests a role in protein sorting, processing, or vesicle-mediated transport pathways essential for secretory function in epithelial cells.
In prostate epithelial cells, which are highly specialized for secretion, proper Golgi function is critical for maintaining cellular polarity and protein export. The presence of SLC45A3 within this compartment highlights its potential contribution to secretory pathway efficiency and epithelial cell physiology. Alterations in Golgi structure and trafficking are known to occur in disease states, including cancer, where changes in protein processing and secretion can influence tumor behavior.
Recombinant Prostein Antibody clone SLC45A3/4965R enables detailed visualization of Golgi-associated structures and supports analysis of intracellular trafficking dynamics in prostate tissue. Its consistent perinuclear staining pattern and strong epithelial localization make it a valuable tool for investigating secretory pathway organization, Golgi morphology, and epithelial cell function in both normal and disease contexts.
Optimal dilution of the Prostein Antibody / Golgi-Associated Secretory Protein Antibody should be determined by the researcher.
The N-terminal region of human SLC45A3/Prostein protein was used as the immunogen for the Prostein Antibody / Golgi-Associated Secretory Protein Antibody.
Aliquot the Prostein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
SLC45A3 antibody, Prostein antibody, Golgi-associated protein antibody, Prostein secretory pathway antibody, SLC45A3 Golgi marker antibody
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