- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Prostatic acid phosphatase Antibody / PAP / PSAP / ACP3 [clone ACPP/4495R] (V5002)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V5002-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
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V5002-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
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V5002SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | ACPP/4495R |
| Purity | Protein A/G affinity |
| UniProt | P15309 |
| Localization | Cytoplasm |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This Prostatic acid phosphatase antibody is available for research use only. |
|
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Prostatic acid phosphatase (ACPP), commonly referred to as PAP or Acid phosphatase 3 (ACP3), is a secreted glycoprotein enzyme highly expressed in prostate epithelial cells. The enzyme belongs to the histidine acid phosphatase family and catalyzes the hydrolysis of phosphomonoesters under acidic conditions. PAP is produced primarily by prostate glandular epithelial cells and is secreted into seminal fluid, where it contributes to enzymatic activity within the prostate microenvironment. Prostatic acid phosphatase Antibody / PAP (clone ACPP/4495R) recognizes this prostate-associated enzyme and enables the detection of Prostatic acid phosphatase expression in prostate-derived tissues and prostate cancer research models.
Prostatic acid phosphatase Antibody is widely used in research investigating prostate epithelial differentiation and prostate cancer biology. In tissue studies, PAP expression is typically localized to prostate glandular epithelial cells and prostate tumor cells. Immunohistochemical detection of Prostatic acid phosphatase often reveals cytoplasmic staining in prostate epithelial structures, reflecting the secretory function of this enzyme within prostate tissue. Because ACP3 expression is strongly associated with prostate epithelial lineage, antibodies directed against PAP are frequently used to evaluate prostate differentiation and identify prostate-derived tumor cells.
Historically, Prostatic acid phosphatase served as one of the earliest biomarkers used in prostate cancer studies prior to the widespread adoption of prostate-specific antigen testing. Although PSA later became the dominant clinical marker, PAP remains an important protein in prostate cancer research and prostate epithelial biology. Analysis of Prostatic acid phosphatase expression provides insight into prostate epithelial differentiation and allows investigators to examine molecular characteristics of prostate tumor tissues.
Prostatic acid phosphatase Antibody (clone ACPP/4495R) is a recombinant rabbit monoclonal antibody developed to recognize PAP in prostate epithelial tissues and prostate cancer models. Antibodies targeting ACP3 are commonly used in studies of prostate gland biology, prostate tumor development, and prostate epithelial cell identity. Detection of PAP expression enables researchers to evaluate prostate lineage markers and examine prostate tumor characteristics in experimental systems.
Research using Prostatic acid phosphatase Antibody supports studies of prostate gland biology, prostate epithelial differentiation, and prostate cancer progression. Examination of ACP3 expression helps identify prostate-derived cells and contributes to understanding the molecular features of prostate tumors in laboratory research.
Optimal dilution of the Prostatic acid phosphatase antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 1-100) from the human protein was used as the immunogen for the Prostatic acid phosphatase antibody.
Aliquot the Prostatic acid phosphatase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
ACP3 antibody, ACPP antibody, Prostate acid phosphatase antibody, PSAP antibody, Prostate specific acid phosphatase antibody
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