Prospero homeobox protein 1 Antibody / PROX1 [clone AOGA-16] (RQ8881)

Description

PROX1 is a homeobox transcription factor that orchestrates cell fate programs by binding target DNA motifs and recruiting co-regulators to modulate chromatin accessibility. It is widely studied for its roles in developmental patterning and maintenance of specialized cell identities, particularly within endothelial and neural lineages.

In vascular biology, PROX1 is a master regulator of lymphatic endothelial specification and maintenance, aligning gene expression with signaling inputs that guide vessel identity, remodeling, and tissue fluid balance. Beyond endothelium, PROX1 contributes to organ development and context-dependent transcriptional networks that shape differentiation, metabolism, and tissue architecture.

The Prospero homeobox protein 1 antibody enables specific detection of endogenous PROX1 in applications such as immunohistochemistry, immunofluorescence, western blot, and immunoprecipitation. Researchers use the Prospero homeobox protein 1 antibody from NSJ Bioreagents to quantify protein abundance, assess nuclear localization, and evaluate pathway engagement across primary tissues and model systems. With high specificity and consistent performance, the Prospero homeobox protein 1 antibody supports rigorous studies of transcriptional regulation, vascular biology, and cell differentiation.

Application Notes

Optimal dilution of the Prospero homeobox protein 1 antibody should be determined by the researcher.

Immunogen

A peptide sequence specific to PROX1 protein was used as the immunogen for the Prospero homeobox protein 1 antibody.

Storage

The Prospero homeobox protein 1 antibody can be stored at -20oC.