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Home >> Antibodies >> Progesterone Antibody

Progesterone Antibody [clone 6-5E-10B] (V3090)

  Catalog No Formulation Size Price (USD)  
Image V3090-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 559
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V3090-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 259
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V3090SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 559
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SDS-PAGE Analysis of Purified, BSA-Free Progesterone Antibody (clone 6-5E-10B). Confirmation of Integrity and Purity of the Antibody.
Molecular Structure of Progesterone
Availability 1-3 business days
Species Reactivity All species
Format Purified
Host Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name 6-5E-10B
Purity Protein G affinity chromatography
Localization Secreted and cytoplasmic
Applications ELISA (order BSA/sodium Azide-free Format For Coating) :
Immunohistochemistry : not tested
Radioimmnoassay (RIA) :
Limitations This Progesterone antibody is available for research use only.
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Description

Progesterone Antibody detects progesterone, a steroid hormone involved in reproductive biology, endocrine regulation and pregnancy maintenance. This monoclonal antibody is specific for progesterone and demonstrates minimal cross-reactivity with related steroid compounds by ELISA analysis. Relative reactivity was observed with Progesterone-11a-HMS-BSA (100%), 5-beta-Pregnane-3,20-dione (48%), 5-alpha-Pregnane-3,20-dione (26.4%), 17-alpha-Hydroxyprogesterone (2.5%) and 20-alpha-Hydroxyprogesterone (0.04%).

Progesterone is synthesized from the cholesterol-derived precursor pregnenolone and is primarily produced by the corpus luteum, adrenal cortex and placenta. As a key reproductive hormone, progesterone regulates endometrial preparation for embryo implantation and contributes to the establishment and maintenance of pregnancy. During pregnancy, placental progesterone production supports uterine function and promotes mammary gland development.

Progesterone signaling plays an important role in ovarian function, reproductive cycles and endocrine system regulation. Measurement and detection of progesterone levels are widely used in reproductive biology research, hormone regulation studies and investigations of endocrine function. Progesterone expression is also studied in relation to hormone-responsive tissues and ovarian tumor research.

Progesterone Antibody applications include detection and analysis of progesterone in biological samples for endocrine and reproductive research. NSJ Bioreagents provides Progesterone Antibody, clone 6-5E-10B, for researchers studying steroid hormones, ovarian biology, pregnancy-associated pathways and hormone-dependent disease models.

Application Notes

Optimal dilution of the Progesterone antibody should be determined by the researcher.

Immunogen

Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA) was used as the immunogen for the Progesterone antibody.

Storage

Store the Progesterone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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