- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Progesterone Antibody detects progesterone, a steroid hormone involved in reproductive biology, endocrine regulation and pregnancy maintenance. This monoclonal antibody is specific for progesterone and demonstrates minimal cross-reactivity with related steroid compounds by ELISA analysis. Relative reactivity was observed with Progesterone-11a-HMS-BSA (100%), 5-beta-Pregnane-3,20-dione (48%), 5-alpha-Pregnane-3,20-dione (26.4%), 17-alpha-Hydroxyprogesterone (2.5%) and 20-alpha-Hydroxyprogesterone (0.04%).
Progesterone is synthesized from the cholesterol-derived precursor pregnenolone and is primarily produced by the corpus luteum, adrenal cortex and placenta. As a key reproductive hormone, progesterone regulates endometrial preparation for embryo implantation and contributes to the establishment and maintenance of pregnancy. During pregnancy, placental progesterone production supports uterine function and promotes mammary gland development.
Progesterone signaling plays an important role in ovarian function, reproductive cycles and endocrine system regulation. Measurement and detection of progesterone levels are widely used in reproductive biology research, hormone regulation studies and investigations of endocrine function. Progesterone expression is also studied in relation to hormone-responsive tissues and ovarian tumor research.
Progesterone Antibody applications include detection and analysis of progesterone in biological samples for endocrine and reproductive research. NSJ Bioreagents provides Progesterone Antibody, clone 6-5E-10B, for researchers studying steroid hormones, ovarian biology, pregnancy-associated pathways and hormone-dependent disease models.
Optimal dilution of the Progesterone antibody should be determined by the researcher.
Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA) was used as the immunogen for the Progesterone antibody.
Store the Progesterone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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