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Home >> Antibodies >> PMEPA1 Antibody / TMEPAI

PMEPA1 Antibody / TMEPAI [clone PTAI1-1] (V7347)

  Catalog No Formulation Size Price (USD)  
Image V7347-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 429
V7347-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 199
V7347SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 429
V7347IHC-7ML Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only* 7 ml 429
IHC staining of FFPE human prostate carcinoma with PMEPA1 antibody (clone PTAI1-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG
Clone Name PTAI1-1
Purity Protein G affinity chromatography
UniProt Q969W9
Localization Cell surface, cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Prediluted IHC only format : incubate for 30 min at RT (1)
Limitations This PMEPA1 antibody is available for research use only.
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PMEPA1 (prostate transmembrane protein, androgen induced 1), or TMEPAI (Transmembrane prostate androgen induced protein) is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Application Notes

Optimal dilution of the PMEPA1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.


Full-length recombinant human protein was used as the immunogen for the PMEPA1 antibody.


Store the PMEPA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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