Platelet Glycoprotein 4 Antibody / Lipid Uptake Protein Antibody [clone CD36/7216] (V5825)

Platelet Glycoprotein 4 Antibody Human Spleen IHC. Immunohistochemical staining of FFPE human spleen demonstrates CD36 expression using Platelet Glycoprotein 4 Antibody clone CD36/7216. Platelet Glycoprotein 4, also known as CD36 and Lipid Uptake Protein, is a class B scavenger receptor involved in fatty acid transport, oxidized lipoprotein uptake, and immune regulation. Prominent membranous staining is observed in splenic macrophages and sinusoidal lining cells, consistent with the known distribution of CD36, while most lymphoid cells exhibit minimal reactivity. The inset shows PBS substituted for the primary antibody as a secondary only negative control. Heat induced epitope retrieval was performed in pH 9 10 mM Tris buffer containing 1 mM EDTA at 95 degrees Celsius for 20 minutes followed by cooling prior to staining. These results support the utility of Platelet Glycoprotein 4 Antibody for studies of lipid metabolism, scavenger receptor biology, inflammation, and immune responses.

Platelet Glycoprotein 4 Antibody Human Heart WB. Western blot analysis of human heart tissue lysate demonstrates CD36 expression using Platelet Glycoprotein 4 Antibody clone CD36/7216. Platelet Glycoprotein 4, also known as CD36 and Lipid Uptake Protein, is a multifunctional scavenger receptor that mediates long chain fatty acid uptake and contributes to cardiac energy metabolism. A prominent band is detected at approximately 90 kDa, consistent with the heavily glycosylated form of CD36. The apparent molecular weight of CD36 is known to vary from approximately 53 to 88 kDa depending on the degree of glycosylation. These results support the utility of Platelet Glycoprotein 4 Antibody for studies of lipid transport, cardiovascular biology, metabolic regulation, and scavenger receptor function.