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Home >> Antibodies >> PLA2R1 Antibody / Phospholipase A2 receptor 1

PLA2R1 Antibody / Phospholipase A2 receptor 1 [clone PLA2R1/4893] (V5697)

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  Catalog No Formulation Size Price (USD)  
Image V5697-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5697-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5697SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4893). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4893). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free PLA2R1 antibody (clone PLA2R1/4893) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2, kappa
Clone Name PLA2R1/4893
Purity Protein A affinity
UniProt Q13018
Localization Cell membrane, Secreted
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This PLA2R1 antibody is available for research use only.
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Description

Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. [UniProt]

Application Notes

Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

Storage

Aliquot the PLA2R1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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