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Home >> Antibodies >> PIAS1/2/3 Antibody

PIAS1/2/3 Antibody [clone ABFA-16] (RQ4791)

  Catalog No Formulation Size Price (USD)  
Image RQ4791 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human HepG2 cell lysate with PIAS1/2/3 antibody. Predicted molecular weight: ~72 kDa (PIAS1) and ~68 kDa (PIAS2 & 3).
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name ABFA-16
Purity Affinity purified
UniProt O75925
Applications Western blot : 1:500-1:2000
Limitations This PIAS1/2/3 antibody is available for research use only.
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Description

Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals. PIAS proteins act as transcriptional co-regulators with at least 60 different proteins in order to either activate or repress transcription. The transcription factors STAT, NF-κB, p73, and p53 are among the many proteins that PIAS interacts with. PIAS proteins have potential applications in cancer treatment and prevention. They may also play an important role in regulating immune system responses. [Wiki]

Application Notes

Optimal dilution of the PIAS1/2/3 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human PIAS 1 & 2 & 3 was used as the immunogen for the PIAS1/2/3 antibody.

Storage

Store the PIAS1/2/3 antibody at -20oC.

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