- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PI16 Antibody / Peptidase inhibitor 16 (RQ6148)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ6148 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat, Monkey |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide |
| UniProt | Q6UXB8 |
| Applications | Western Blot : 1-2ug/ml Immunohistochemistry (FFPE) : 2-5ug/ml Flow Cytometry : 1-3ug/million cells Direct ELISA : 0.1-0.5ug/ml |
| Limitations | This PI16/Peptidase inhibitor 16 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
PI16 Antibody recognizes Peptidase inhibitor 16, also known as PI16 and Peptidase inhibitor 16 precursor, a secreted cysteine-rich protein implicated in extracellular protease regulation and tissue homeostasis. Peptidase inhibitor 16 is sometimes referred to in the literature as CRISP-like protein 1 due to its cysteine-rich secretory protein domain structure. PI16 Antibody is commonly described as Peptidase inhibitor 16 antibody and is used in studies focused on extracellular matrix regulation, protease activity, and stromal biology.
Peptidase inhibitor 16 is primarily expressed in fibroblasts, stromal cells, and certain endothelial and mesenchymal cell populations. As a secreted protein, PI16 is localized to the extracellular space and is associated with modulation of proteolytic activity within the tissue microenvironment. Through regulation of protease signaling pathways, PI16 has been implicated in controlling extracellular matrix remodeling, tissue repair processes, and cellular migration. Expression patterns are often observed in connective tissue-rich organs and in stromal compartments adjacent to epithelial or vascular structures.
Altered PI16 expression has been investigated in cardiovascular biology, fibrosis, inflammatory conditions, and tumor microenvironment studies. Changes in Peptidase inhibitor 16 levels have been associated with tissue remodeling and stromal activation, particularly in heart and skeletal muscle research. In oncology research, PI16-positive stromal cells may be examined in the context of tumor-stroma interactions and extracellular matrix dynamics. Consequently, PI16 antibody staining is frequently evaluated in studies examining fibroblast biology, protease regulation, and tissue remodeling pathways.
At the molecular level, Peptidase inhibitor 16 contains characteristic cysteine-rich domains that are thought to influence protein-protein interactions and extracellular signaling. Its role as a secreted regulator of protease activity makes PI16 Antibody a valuable tool for investigating extracellular matrix biology, stromal cell populations, and tissue remodeling mechanisms in normal and diseased tissues.
Optimal dilution of the PI16/Peptidase inhibitor 16 antibody should be determined by the researcher.
A human recombinant partial protein (amino acids L28-L363) was used as the immunogen for the PI16/Peptidase inhibitor 16 antibody.
After reconstitution, the PI16/Peptidase inhibitor 16 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
