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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq].
Titration of the PHOX2B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 104-130 from the human protein was used as the immunogen for this PHOX2B antibody.
Aliquot the PHOX2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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