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- Tel: 858.663.9055
- Email: info@nsjbio.com
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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Titration of the phosphorylated-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This phosphorylated-SOX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS251 of human SOX2.
Aliquot the phosphorylated-SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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