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Home >> Antibodies >> Phospho-PDGFRB Antibody (pY740)

Phospho-PDGFRB Antibody (pY740) [clone FDF-16] (RQ5285)

  Catalog No Formulation Size Price (USD)  
Image RQ5285 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of lysate from PDGF-treated mouse NIH3T3 cells with phospho-PDGFRB antibody (pY740). Expected molecular weight: 123-190 kDa depending on level of glycosylation.
Availability 1-2 weeks
Species Reactivity Mouse
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name FDF-16
Purity Affinity purified
UniProt P09619
Applications Western blot : 1:1000-1:2000
Limitations This phospho-PDGFRB antibody (pY740) is available for research use only.
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Description

The protein encoded by the PDGFRB gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. [RefSeq]

Application Notes

Optimal dilution of the phospho-PDGFRB antibody (pY740) should be determined by the researcher.

Immunogen

A synthetic peptide specific to PDGF Receptor beta (surrounding phosphorylated Y740) was used as the immunogen for the phospho-PDGFRB antibody.

Storage

Store the phospho-PDGFRB antibody (pY740) at -20oC.

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