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Home >> Antibodies >> Phospho-ILK Antibody (pS343)

Phospho-ILK Antibody (pS343) (F48615)

  Catalog No Formulation Size Price (USD)  
Image F48615-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48615-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Dot blot analysis of phospho ILK antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q13418
Applications Dot blot : 1:500
Limitations This phospho-ILK antibody is available for research use only.
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Description

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

Application Notes

Titration of the phospho-ILK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This phospho-ILK antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS343 of human ILK.

Storage

Aliquot the phospho-ILK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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