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- Tel: 858.663.9055
- Email: info@nsjbio.com
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ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Titration of the phospho-ERK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This phospho-ERK3 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS189 of human ERK3.
Aliquot the phospho-ERK3 antibody (phospho-S189 and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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