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- Email: info@nsjbio.com
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ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Titration of the phospho-ATF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This phospho-ATF2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS322 of human ATF2.
Aliquot the phospho-ATF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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