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Home >> Antibodies >> Periaxin Antibody / PRX

Periaxin Antibody / PRX (RQ4326)

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  Catalog No Formulation Size Price (USD)  
Image RQ4326 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat kidney, 2) mouse kidney, 3) human 293T and 4) human HK-2 lysate with Periaxin antibody at 0.5ug/ml. Predicted molecular weight ~155 kDa.
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Western blot testing of 1) rat kidney, 2) mouse kidney, 3) human 293T and 4) human HK-2 lysate with Periaxin antibody at 0.5ug/ml. Predicted molecular weight ~155 kDa.
Flow cytometry testing of human K562 cells with Periaxin antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=Periaxin antibody.
Flow cytometry testing of human A549 cells with Periaxin antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=Periaxin antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9BXM0
Localization Cell membrane
Applications Western blot : 0.5-1ug/ml
Flow Cytometry : 1-3ug/10^6 cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Periaxin antibody is available for research use only.
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Description

Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Application Notes

Optimal dilution of the Periaxin antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids M1-K91 was used as the immunogen for the Periaxin antibody.

Storage

After reconstitution, the Periaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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