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Home >> Antibodies >> PDS5B Antibody / AS3

PDS5B Antibody / AS3 (F53857)

  Catalog No Formulation Size Price (USD)  
Image F53857-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F53857-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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Western blot testing of human 1) 293T/17, 2) DU-145, 3) LNCaP, 4) Raji, 5) U-2OS and 6) HeLa cell lysate with PDS5B antibody at 1:2000. Predicted molecular weight: 165 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NTI5
Applications Western blot : 1:1000-2000
Limitations This PDS5B antibody is available for research use only.
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    Reactivity : Human, Mouse

Description

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

Application Notes

Titration of the PDS5B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1197-1228 from the human protein was used as the immunogen for the PDS5B antibody.

Storage

Aliquot the PDS5B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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