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Home >> Antibodies >> PDK2 Antibody / Pyruvate dehydrogenase kinase 2

PDK2 Antibody / Pyruvate dehydrogenase kinase 2 (RQ4125)

  Catalog No Formulation Size Price (USD)  
Image RQ4125 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat 1) heart, 2) skeletal muscle, 3) brain, 4) kidney and mouse 5) heart, 6) skeletal muscle, 7) brain and 8) kidney lysate with PDK2 antibody at 0.5ug/ml. Predicted molecular weight ~46 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q15119
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This PDK2 antibody is available for research use only.
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Description

PDK2 (Pyruvate Dehydrogenase Kinase Isoenzyme 2), is an enzyme that in humans is encoded by the PDK2 gene. This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Application Notes

Optimal dilution of the PDK2 antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein corresponding to amino acids V81-D177 was used as the immunogen for the PDK2 antibody.

Storage

After reconstitution, the PDK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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