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Home >> Antibodies >> PDHB Antibody / Pyruvate Dehydrogenase E1 beta subunit

PDHB Antibody / Pyruvate Dehydrogenase E1 beta subunit [clone AEAD-16] (RQ5355)

  Catalog No Formulation Size Price (USD)  
Image RQ5355 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
Microvalidated Rab Mono Image
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Western blot testing of human HeLa cell lysate with PDHB antibody. Predicted molecular weight ~39 kDa.
Availability 1-2 weeks
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AEAD-16
Purity Affinity purified
UniProt P11177
Applications Western blot : 1:1000-1:5000
Limitations This PDHB antibody is available for research use only.
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Description

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. [RefSeq]

Application Notes

Optimal dilution of the PDHB antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Pyruvate Dehydrogenase E1 beta subunit / PDHB was used as the immunogen for the PDHB antibody.

Storage

Store the PDHB antibody at -20oC.

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