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Home >> Antibodies >> PDGFRA Antibody / Platelet Derived Growth Factor Receptor alpha

PDGFRA Antibody / Platelet Derived Growth Factor Receptor alpha [clone AAOE-16] (RQ5478)

  Catalog No Formulation Size Price (USD)  
Image RQ5478 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing of human SH-SY5Y cell lysate with PDGFRA antibody. Expected molecular weight: 120-195 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AAOE-16
Purity Affinity purified
UniProt P16234
Applications Western blot : 1:500-1:2000
Limitations This PDGFRA antibody is available for research use only.
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Description

The PDGFRA gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [RefSeq]

Application Notes

Optimal dilution of the PDGFRA antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human PDGFR alpha / PDGFRA was used as the immunogen for the PDGFRA antibody.

Storage

Store the PDGFRA antibody at -20oC.

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