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Home >> Antibodies >> PDGFR Antibody (CD140b)

PDGFR Antibody (CD140b) [clone 275CT1] (F40302)

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  Catalog No Formulation Size Price (USD)  
Image F40302-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40302-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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PDGFR antibody western blot analysis in mouse NIH3T3 lysate. Expected molecular weight: 123-190 kDa depending on level of glycosylation.
PDGFR antibody western blot analysis in mouse NIH3T3 lysate. Expected molecular weight: 123-190 kDa depending on level of glycosylation.
Availability 1-3 business days
Species Reactivity Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, k
Clone Name 275CT1
Purity Purified
UniProt P09619
Applications Western blot : 1:8-1:30
Limitations This PDGFR antibody is available for research use only.
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Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].

Application Notes

Titration of the PDGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This PDGFR antibody was produced from a mouse immunized with recombinant protein.

Storage

Aliquot the PDGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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