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Home >> Antibodies >> PDGF-B Antibody

PDGF-B Antibody (R31724)

  Catalog No Formulation Size Price (USD)  
Image R31724 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of PDGF-B antibody and Lane 1: rat heart; 2: (r) brain; 3: mouse heart; 4: human HeLa lysate Predicted size: ~15 kDa monomer and ~32 kDa dimer.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Gene ID 5155
Applications Western blot : 0.5-1ug/ml
Limitations This PDGF-B antibody is available for research use only.
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Description

Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. PDGF-B can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGF-B plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGF-A.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the PDGF-B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 82-190) was used as the immunogen for this PDGF-B antibody.

Storage

After reconstitution, the PDGF-B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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