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Home >> Antibodies >> PD1 Antibody / PDCD1

PD1 Antibody / PDCD1 [clone PDCD1/7276R] (V4967)

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  Catalog No Formulation Size Price (USD)  
Image V4967-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4967-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4967SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human tonsil tissue with PD1 (CD279) antibody (clone PDCD1/7276R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human tonsil tissue with PD1 (CD279) antibody (clone PDCD1/7276R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human tonsil tissue with PD1 (CD279) antibody (clone PDCD1/7276R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name PDCD1/7276R
Purity Protein A/G affinity
UniProt Q15116
Localization Cell surface, Cytoplasm
Applications ELISA (Order BSA-free format for coating) :
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This PD1 antibody is available for research use only.
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Description

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Application Notes

Optimal dilution of the PD1 antibody should be determined by the researcher.

Immunogen

A recombinant fragment corresponding to the extracellular domain of human PDCD1 protein was used as the immunogen for the PD1 antibody.

Storage

Aliquot the PD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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