- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PD-L1 Antibody [clone PDL1/2746] (V3955PE)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V3955PE-100T | 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 Tests | 519 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | PE Conjugate |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b, kappa |
| Clone Name | PDL1/2746 |
| Purity | Protein G affinity chromatography |
| UniProt | Q9NZQ7 |
| Localization | Cell surface, cytoplasmic |
| Applications | Flow cytometry : 1-2ug/million cells in 0.1ml Immunofluorescence : 1-2ug/ml |
| Limitations | This PD-L1 antibody is available for research use only. |
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PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Optimal dilution of the PD-L1 antibody should be determined by the researcher.
A portion of amino acids 39-191 from the human protein was used as the immunogen for this PD-L1 antibody.
Store the PD-L1 antibody at 2-8oC, protected from light.
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