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Home >> Antibodies >> PCSK9 Antibody

PCSK9 Antibody (F50317)

  Catalog No Formulation Size Price (USD)  
Image F50317-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 369
Image
F50317-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 149
Western blot analysis of lysate from HeLa cell line using PCSK9 antibody. Predicted size: Pro/mature ~74/64 kDa
Western blot analysis of lysate from HepG2, HeLa, SW480 cell line using PCSK9 antibody. Predicted size: Pro/mature ~74/64 kDa
Western blot analysis of lysate from SW480 cell line using PCSK9 antibody. Predicted size: Pro/mature ~74/64 kDa
Immunohistochemical analysis of paraffin-embedded human colorectal carcinoma section using PCSK9 antibody
Flow cytometric analysis of HeLa cells using PCSK9 antibody (green) compared to an isotype control of rabbit IgG (blue); Ab was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG was used as the secondary Ab.
Flow cytometric analysis of A431 cells using PCSK9 antibody (green) compared to an isotype control of rabbit IgG (blue). Ab was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG was used as the secondary Ab.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q8NBP7
Applications Flow Cytometry : 1:25
IHC (Paraffin) : 1:25
Western blot : 1:1000
Limitations This PCSK9 antibody is available for research use only.
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Description

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Application Notes

Titration of the PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 144-173 from the human protein was used as the immunogen for this PCSK9 antibody.

Storage

Aliquot the PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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