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Home >> Antibodies >> PBP Antibody / PEBP1 / RKIP

PBP Antibody / PEBP1 / RKIP (F54962)

  Catalog No Formulation Size Price (USD)  
Image F54962-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54962-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of human Y79 cell lysate with PBP antibody. Predicted molecular weight ~21 kDa.
Western blot testing of human HeLa cell lysate with PBP antibody. Predicted molecular weight ~21 kDa.
IHC testing of FFPE human hepatocellular carcinoma tissue with PBP antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
IHC testing of FFPE human cancer tissue with PBP antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P30086
Localization Cytoplasmic
Applications Immunohistochemistry (FFPE) : 1:50-1:100
Western blot : 1:500-1:1000
Limitations This PBP antibody is available for research use only.
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Description

PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.

Application Notes

The stated application concentrations are suggested starting points. Titration of the PBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for the PBP antibody.

Storage

Aliquot the PBP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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