- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PAX6 Antibody Mouse Monoclonal PAX6/7707 [clone PAX6/7707] (V4134)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V4134-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V4134-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
|
V4134SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG |
| Clone Name | PAX6/7707 |
| Purity | Protein A/G affinity |
| UniProt | P26367 |
| Localization | Nucleus |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT |
| Limitations | This PAX6 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
Paired box protein Pax-6 (PAX6) is a nuclear transcription factor encoded by the PAX6 gene and functions as a master regulator of eye development and neural differentiation. The protein belongs to the paired box family of transcription factors and controls transcriptional programs that regulate tissue patterning, neuronal specification, and organogenesis. PAX6 Antibody Mouse Monoclonal PAX6/7707 recognizes Pax-6 and supports research investigating transcriptional regulation during embryonic development and neural lineage commitment.
PAX6 plays a critical role during embryogenesis in formation of the retina, lens, cornea, and other ocular structures. The transcription factor is also expressed in neural progenitor cells within the developing brain where it contributes to regional patterning of the cerebral cortex and differentiation of neuronal populations. Because of its essential developmental functions, Pax-6 expression is frequently examined in studies of neurogenesis, stem cell biology, and developmental signaling pathways.
The PAX6 protein contains multiple functional domains responsible for DNA binding and transcriptional regulation. An N-terminal paired domain binds specific DNA sequences within regulatory regions of target genes. A homeodomain provides additional DNA-binding capability, and the C-terminal proline-serine-threonine rich transactivation domain interacts with transcriptional co-regulators to activate gene expression. Through these domains Pax-6 coordinates transcription of genes involved in cellular differentiation and tissue morphogenesis.
Mouse monoclonal antibodies provide highly specific detection of target proteins by recognizing a single epitope on the antigen. PAX6 Antibody Mouse Monoclonal PAX6/7707 therefore enables precise detection of Pax-6 protein and supports reproducible results in experimental systems where consistent epitope recognition is required. Monoclonal antibodies are frequently used for studies examining transcription factor expression and localization across different biological samples.
PAX6 antibody reagents are commonly described in the literature using several related names including PAX6 antibody, Pax-6 antibody, paired box protein Pax-6 antibody, and aniridia type II protein antibody. These terms all refer to the transcription factor encoded by the PAX6 gene. PAX6 Antibody Mouse Monoclonal PAX6/7707 recognizes Pax-6 protein and supports research focused on transcriptional regulation, developmental gene networks, and neural differentiation pathways.
Optimal dilution of the PAX6 Antibody Mouse Monoclonal PAX6/7707 should be determined by the researcher.
A recombinant partial protein (within amino acids 1-300) from the human protein was used as the immunogen for the PAX6 antibody.
Aliquot the PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Pax-6 antibody, paired box protein Pax-6 antibody, aniridia type II protein antibody, Pax6 transcription factor antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
