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Home >> Antibodies >> PAX6 Antibody

PAX6 Antibody [clone 193CT15.2.2] (F53525)

  Catalog No Formulation Size Price (USD)  
Image F53525-0.1ML In ascites with 0.09% sodium azide 0.1 ml 399
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PAX6 antibody western blot analysis in 293 lysate. Predicted molecular weight ~48kDa.
Confocal immunofluorescent analysis of PAX6 antibody with HeLa cells followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). Actin filaments have been labeled with Alexa Fluor 555 Phalloidin (red). DAPI was used as a nuclear counterstain (blue).
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Bovine
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgM, k
Clone Name 193CT15.2.2
Purity Ascites
UniProt P26367
Applications Western blot : 1:500-1:16000
Immunofluorescence : 1:10-1:50
Limitations This PAX6 antibody is available for research use only.
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Description

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].

Application Notes

Titration of the PAX6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This PAX6 antibody was raised using purified His-tagged recombinant human PAX6.

Storage

Aliquot the PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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