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Home >> Antibodies >> Parathyroid Hormone Receptor 1 Antibody / PTH1R

Parathyroid Hormone Receptor 1 Antibody / PTH1R (RQ7303)

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  Catalog No Formulation Size Price (USD)  
Image RQ7303 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of human HEL cells with Parathyroid Hormone Receptor 1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Parathyroid Hormone Receptor 1 antibody.
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Flow cytometry testing of human HEL cells with Parathyroid Hormone Receptor 1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Parathyroid Hormone Receptor 1 antibody.
Western blot testing of 1) human 293T, 2) human HepG2, 3) human HUH-7 and 4) monkey COS-7 cell lysate with Parathyroid Hormone Receptor 1 antibody. Expected molecular weight ~66 kDa (unmodified), 85-95 kDa (glycosylated).
Availability 1-3 business days
Species Reactivity Human, Monkey
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q03431
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Parathyroid Hormone Receptor 1 antibody is available for research use only.
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Description

Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.

Application Notes

Optimal dilution of the Parathyroid Hormone Receptor 1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids R102-L446) was used as the immunogen for the Parathyroid Hormone Receptor 1 antibody.

Storage

After reconstitution, the Parathyroid Hormone Receptor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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