- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor). PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
A recombinant protein fragment from the intermal portion of human PACS-1 was used as the immunogen for this antibody.
Aliquot the PACS-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Phosphofurin acidic cluster sorting protein 1 antibody
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