- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PACAP Antibody / Adenylate Cyclase Activating Polypeptide Antibody (R34103)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
R34103-100UG | 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide | 100 ug | 475 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Pig, Cow |
| Format | Antigen affinity purified |
| Host | Goat |
| Clonality | Polyclonal (goat origin) |
| Isotype | Goat Ig |
| Purity | Antigen affinity |
| Gene ID | 116 |
| Applications | Western Blot : 1-3ug/ml ELISA (peptide) LOD : 1:2000 |
| Limitations | This PACAP antibody is available for research use only. |
|
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PACAP Antibody / Adenylate Cyclase Activating Polypeptide Antibody recognizes pituitary adenylate cyclase activating polypeptide (PACAP), a highly conserved neuropeptide encoded by the ADCYAP1 gene. Following proteolytic processing of its precursor protein, PACAP is produced primarily as the biologically active PACAP-38 and PACAP-27 peptides, which function through PAC1, VPAC1, and VPAC2 receptors to regulate cyclic AMP-dependent signaling. PACAP is expressed throughout the central and peripheral nervous systems as well as in endocrine, gastrointestinal, and reproductive tissues. A PACAP Antibody provides an important tool for studying neuropeptide signaling and neuroendocrine regulation.
Adenylate Cyclase Activating Polypeptide participates in numerous physiological processes including neurotransmission, hormone secretion, neuronal differentiation, synaptic plasticity, circadian rhythm regulation, and cellular survival. The peptide also influences immune responses, vascular function, metabolism, and gastrointestinal activity. Because PACAP expression changes in response to neuronal injury and cellular stress, it has become an important biomarker for investigations of neuroprotection, tissue repair, and adaptive signaling mechanisms.
Abnormal PACAP signaling has been associated with migraine, neurodegenerative disease, ischemic injury, psychiatric disorders, chronic pain, inflammation, metabolic dysfunction, and several cancers. PACAP antibodies are suitable for applications including Western blotting and related protein detection methods when validated for the specific application. NSJ Bioreagents provides carefully validated antibodies to support investigations of neuropeptide biology, neuronal signaling, neuroendocrine function, and disease-associated cellular pathways. A PACAP Antibody / Adenylate Cyclase Activating Polypeptide Antibody is a valuable research reagent for detecting PACAP expression and advancing studies of nervous system function and neuroprotective signaling.
Visit our ADCYAP1 Antibody / Pituitary Adenylate Cyclase Activating Polypeptide Antibody page to explore additional validated antibodies and research tools for investigating ADCYAP1 expression, PACAP signaling, neuropeptide biology, neuroendocrine regulation, and nervous system function.
Optimal dilution of the PACAP Antibody / Adenylate Cyclase Activating Polypeptide Antibody should be determined by the researcher.
Amino acids GKRYKQRVKNKGRR were used as the immunogen for this PACAP antibody.
Aliquot and store the PACAP antibody at -20oC.
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