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- Email: info@nsjbio.com
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Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of cyclin D-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Titration of the p27Kip1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 175-197 from the mouse protein was used as the immunogen for this p27Kip1 antibody.
Aliquot the p27Kip1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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