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- Tel: 858.663.9055
- Email: info@nsjbio.com
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p16(INK4A), also known as cyclin-dependent kinase inhibitor 2A(CDKN2A), or multiple tumor suppressor 1(MTS1). The p16 gene(CDKN2A) was mapped to 9p21. The p16 gene encodes a negative regulator of the cell cycle. CDKN2 plays an important role during tumorigenesis or tumor progression in a significant proportion of pancreatic adenocarcinomas. Germ-line mutations in the CDKN2A tumor-suppressor gene have been linked to the development of melanoma in some families with inherited melanoma.
The stated application concentrations are suggested starting amounts. Titration of the p16INK4a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Recombinant human p16 protein was used as the immunogen for this p16INK4a antibody.
After reconstitution, the p16INK4a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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