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  • Email: info@nsjbio.com
Home >> Antibodies >> p16INK4a Antibody

p16INK4a Antibody (F53421)

  Catalog No Formulation Size Price (USD)  
F53421-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329

F53421-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot testing of p16INK4a antibody at 1:2000 dilution + HeLa lysate; Predicted molecular weight: 17 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P42771
Applications Western blot : 1:2000
Limitations This p16INK4a antibody is available for research use only.
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Description

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Application Notes

Titration of the p16INK4a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This p16INK4a antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from human p16-INK4a.

Storage

Aliquot the p16INK4a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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