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Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Optimal dilution of the OPA1 antibody should be determined by the researcher.
A synthetic peptide specific to human OPA1 was used as the immunogen for the OPA1 antibody.
Store the OPA1 antibody at -20oC.
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