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Home >> Antibodies >> Olig1 Antibody

Olig1 Antibody (R31337)

  Catalog No Formulation Size Price (USD)  
Image R31337 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Olig1 antibody and Lane 1: U87; 2: HeLa lysate
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q8TAK6
Applications Western blot : 0.5-1ug/ml
Limitations This Olig1 antibody is available for research use only.
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Description

Oligodendrocyte transcription factor 1, also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that Olig1 is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. Olig1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with Olig2 to establish the pMN domain of the embryonic neural tube.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Olig1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the N-terminus of human Oligodendrocyte transcription factor 1 (ARPDAKEEQQQQLRRK) was used as the immunogen for this Olig1 antibody.

Storage

After reconstitution, the Olig1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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