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Home >> Antibodies >> NUR77 Antibody

NUR77 Antibody (F49565)

  Catalog No Formulation Size Price (USD)  
Image F49565-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49565-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot analysis of NUR77 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the NR4A1 gene (2). Predicted molecular weight ~64/66kDa (isoforms 1/2).
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P22736
Applications Western blot : 1:1000
Limitations This NUR77 antibody is available for research use only.
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Description

NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.

Application Notes

Titration of the NUR77 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. This Ab will detect isoforms 1 and 2.

Immunogen

A portion of amino acids 329-358 from human NR4A1 was used as the immunogen for this NUR77 antibody. (1)

Storage

Aliquot the NUR77 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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